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Antigone S. Dimas on Muck Rack

Antigone S. Dimas

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Articles

Diet-responsive proteogenomic effects following short-term restriction of animal products in humans

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By Alexandros Simistiras, Ozvan Bocher, Christina Emmanouil, Anargyros Skoulakis, Stavros Glentis, Nikolaos Scarmeas, Eleftheria Zeggini, Konstantinos Rouskas, Antigone S. Dimas
| Nature Verified
Abstract The effect of diet on genetic regulation in humans remains largely unexplored. Here, we investigate gene-diet interactions in a unique group of healthy individuals (N = 200) who alternate between omnivory and dietary restriction of animal products for religious reasons. Using longitudinal proteomic and genotype data, we identify diet-responsive cis-pQTLs and highlight regulatory effects on LBR and MSRA, proteins involved in cholesterol and methionine metabolism respectively.
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