Antje Margret Wengner on Muck Rack

Antje Margret Wengner

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Articles

Mes/Stem-A ovarian cancer subtypes predict sensitivity to ATR inhibition

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By Vignesh Sundararajan, Tuan Zea Tan, Antje Margret Wengner, Maili Qi, Chit Fang Cheok, Fang Ziyu, Gamal Ahmed Elfar, Kuee Theng Kuay, Agnes Tan, Clemence Lai
| Nature Verified
Abstract High-grade serous ovarian cancer (HGSOC) remains one of the most common and lethal gynecological malignancies. Distinct gene expression molecular subtypes (GEMS) of HGSOC, with associated differences in outcome, have previously been described: Epithelial-A (Epi-A)/C3/Differentiated, Epithelial-B (Epi-B)/C2/Immunoreactive, Stem-like B (Stem-B)/C6, Mesenchymal (Mes)/C1, and Stem-like A (Stem-A)/C5/Proliferative.
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