António Barbosa

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Abstract The biogenesis of membrane-bound organelles involves the synthesis, remodelling and degradation of their constituent phospholipids. How these pathways regulate organelle size, remains still poorly understood. Here we demonstrate that a lipid degradation pathway inhibits the expansion of the endoplasmic reticulum (ER) membrane. Phospholipid diacylglycerol acyltransferases (PDATs) use endogenous phospholipids as fatty acyl donors to generate triglyceride stored in lipid droplets.

The Urbanistic SIMPLEX arrives in March, with some rules taking effect retroactively to January 1st, and aims to introduce a profound paradigm shift in urban planning and management. The objective of this change is to contribute to the end of the crisis in housing. And put an end to it by increasing the supply of available construction through several routes. The Decree-Law no.