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Anub M. Thomas

As seen in: The Journal of Immunology
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Articles

Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood

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By Anub M. Thomas, Alexandra Gerogianni, Martin McAdam, Yngvar Fløisand
| The Journal of Immunology Verified
Open Access Anub M. Thomas, Alexandra Gerogianni, Martin B. McAdam, Yngvar Fløisand, Corinna Lau, Terje Espevik, Per H. Nilsson, Tom Eirik Mollnes and Andreas Barratt-Due J Immunol September 15, 2019, 203 (6) 1571-1578; DOI: https://doi.org/10.4049/jimmunol.1900047 Key Points Heme induces complement-dependent thromboinflammation in human whole blood. Heme-induced proinflammatory cytokines and tissue factor are C5 dependent. Combined inhibition of C5 and CD14 attenuate prothrombin cleavage.
Open in Who Shared Issue with article?

Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood

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By Martin McAdam, Anub M. Thomas, Alexandra Gerogianni, Yngvar Fløisand
| The Journal of Immunology Verified
Open Access Anub M. Thomas, Alexandra Gerogianni, Martin B. McAdam, Yngvar Fløisand, Corinna Lau, Terje Espevik, Per H. Nilsson, Tom Eirik Mollnes and Andreas Barratt-Due J Immunol August 14, 2019, ji1900047; DOI: https://doi.org/10.4049/jimmunol.1900047 Key Points Heme induces complement-dependent thromboinflammation in human whole blood. Heme-induced proinflammatory cytokines and tissue factor are C5 dependent. Combined inhibition of C5 and CD14 attenuate prothrombin cleavage.
Open in Who Shared Issue with article?
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