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Anuradha Pandit on Muck Rack

Anuradha Pandit

As seen in: BioRxiv
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Articles

Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression

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By Sk Kayum Alam, Li Wang, Anuradha Pandit, Brittney A. Thiele
| BioRxiv
Abstract Small cell lung cancer (SCLC) is difficult to treat due to its aggressiveness, early metastasis, and rapid development of resistance to chemotherapeutic agents. Here, we show that treatment with a dopamine D2 receptor (D2R) agonist reduces tumour angiogenesis in multiple in vivo xenograft models of human SCLC, thereby reducing SCLC progression.
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