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Anusha Bargavi Gopalan on Muck Rack

Anusha Bargavi Gopalan

As seen in: BioRxiv
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Articles

Caging of membrane-to-cortex attachment proteins can trigger cellular symmetry breaking

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By Ruben Moreno, Rubén Moreno, Ivan Palaia, Srishti Dar, Anusha Bargavi Gopalan
| BioRxiv
Abstract To migrate, divide, and change shape, cells must regulate the mechanics of their periphery. The cell surface is a complex structure that consists of a thin, contractile cortical actin network tethered to the plasma membrane by specialized membrane-to-cortex attachment (MCA) proteins. This active and constantly fluctuating system maintains a delicate mechanochemical state which permits spontaneous polarization and shape change when needed.
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