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April L. Raftery on Muck Rack

April L. Raftery

As seen in: MDPI, Science Magazine
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Articles

Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen

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By Helen Stölting, Ming-Ting Tsai, April L. Raftery, Simone A. Walker, Eimear N Rutherford, Yue Huang, Franz Puttur, Laura Yates, Sejal Saglani, Clare M. Lloyd, Mindy L. Gore
| Science Magazine Verified
Editor’s summary The frequency and severity of asthma are higher in adult females compared with males, and periods of hormonal change—such as puberty, pregnancy, and menopause—are associated with the modulation of symptoms. Stölting et al. report that female mice exposed to house dust mite (HDM) aeroallergens starting early in life show enhanced type 2 airway responses compared with males. The female hormone 17β-estradiol (E2) amplifies the production of interleukin-33 (IL-33) by fibroblasts.
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Regulation of Microglial Signaling by Lyn and SHIP-1 in the Steady-State Adult Mouse Brain

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By Richelle Mychasiuk, Evelyn Tsantikos, Erskine Chu, April L. Raftery
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
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