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April M. Barbour on Muck Rack

April M. Barbour

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Single Dose Euglycemic Clamp Studies Demonstrating Pharmacokinetic and Pharmacodynamic Similarity Between MK-1293 Insulin Glargine and Originator Insulin Glargine (Lantus) in Type 1 Diabetes and Healthy Subjects - Crutchlow - 2017 - Diabetes, Obesity and

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By Michael Marcos, Yang Xu, Linda A. Morrow, Marcus Hompesch, Michael Crutchlow, John S. Palcza, Kate M. Mostoller, Chantal D. Mahon, April M. Barbour, Elaine Watkins
| Color Research & Application Verified
MK-1293 is an insulin glargine that has an identical amino acid sequence to that of Lantus, the originator insulin glargine. Two euglycemic clamp studies, one in subjects with Type 1 diabetes (T1D) and one in healthy subjects, were conducted to demonstrate pharmacokinetic (PK) and pharmacodynamic (PD) similarity between MK-1293 and Lantus commercially procured in both the European Union (EU-Lantus) and United States (US-Lantus).
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