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Areej Ibrahim Alshayea on Muck Rack

Areej Ibrahim Alshayea

As seen in: BioRxiv
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Articles

Wild-type and single-O-antigen repeat outer-membrane vesicles induce equivalent protection against homologous and heterologous Salmonella challenge

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By Sian E. Jossi, Edith Marcial-Juárez, Marisol Pérez-Toledo, Areej Ibrahim Alshayea
| BioRxiv
Abstract Lipopolysaccharide O-antigen is an immunodominant target of protective antibodies. Variation in O-antigen structures limits antibody-mediated cross-protection between closely-related pathogens including Salmonella Typhimurium (STm) and S. Enteritidis (SEn). Bacterial outer membrane vesicles (OMV) are vaccine platforms presenting surface antigens in their natural conformations.
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