Arens Taga

1 Part I: History of Presenting Illness A 73-year-old man presented with a five-year history of gradually progressive muscle weakness. Initially, he experienced difficulty climbing stairs and frequent tripping due to left-sided foot dorsiflexion weakness. Over time, this progressed to bilateral hand weakness, particularly impairing grip strength and dexterity. He denied sensory loss, dysphagia, dyspnea, or constitutional symptoms. He had not noted rashes, arthralgias, or respiratory symptoms.

Abstract The chromosome 15q11.2 locus is deleted in 1.5% of patients with genetic epilepsy and confers a risk for intellectual disability and schizophrenia. Individuals with this deletion demonstrate increased cortical thickness, decreased cortical surface area and white matter abnormalities.

New Results Akshata A. Almad, Arens Taga, Jessica Joseph, Connor Welsh, Aneesh Patankar, Sarah K. Gross, Jean-Philippe Richard, Aayush Pokharel, Mauricio Lillo, Raha Dastgheyb, Kevin Eggan, Norman Haughey, Jorge E. Contreras, Nicholas J.