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Ariane Schaub Clarigue on Muck Rack

Ariane Schaub Clarigue

As seen in: BioRxiv
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Articles

Secreted spermidine synthase reveals a paracrine role for PGC1a-induced growth suppression in prostate cancer

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By Alice Macchia, Ariane Schaub Clarigue, Ivana Hermanova, Ainara Pintor Rial
| BioRxiv
Abstract Prostate cancer is the fifth cause of death by cancer worldwide, second in incidence in the male population. The definition of the molecular basis of its development and the oncogenic signals driving lethality continue to be important objectives in prostate cancer research. Prior work from others and us has demonstrated that loss of PGC1α expression results in a metabolic, signaling and transcriptional reprogramming that supports the development of metastatic disease.
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