Aristea Papageorgiou

Response to: ‘Is miR200b-5p a new predictor of lymphoma or associated with lymphocytes infiltrate within salivary glands?’ by Nocturne et al Efstathia K Kapsogeorgou1,2, Aristea Papageorgiou1, Athanase D Protogerou1,2, Michael Voulgarelis1,2, Athanasios G Tzioufas1,2 1 Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece 2 Academic Joint Rheumatology Program, School of Medicine, National and Kapodistrian University of Athens,...

We would like to thank Nocturne et al1 for their comments regarding our paper,2 giving us the opportunity to clarify possible obscurities and signify the predictive value of low miR200b-5p levels in minor salivary glands (MSGs) for the development of lymphoma in primary Sjögren’s syndrome (pSS).

Objectives Development of non-Hodgkin’s lymphoma (NHL) is the major adverse outcome of Sjögren’s syndrome (SS) affecting both morbidity and mortality. Preliminary evidence suggested that, although not deregulated compared with sicca controls, miR200b-5p levels are decreased in the minor salivary glands (MSGs) of SS patients with NHL.