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Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models

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By András Rókusz, Dániel Veres, Armanda Szücs, Edina Bugyik
| PLOS
The stringent connection between ductular reaction and fibrosis, which cannot be influenced by any of our treatment regimens, suggests that there is a close mutual interaction between them instead of a unidirectional causal relationship. Our results confirm a close connection between DR and fibrogenesis. However, since the two parameters changed together we could not establish a causal relationship and were unable to reveal which was the primary event.
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