Arnab Chowdhury

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Abstract Borylated compounds have received tremendous attention in chemical biology and drug design. Motivated by this notion, we develop an efficient methodology for boron incorporation into peptides and proteins via chemoselective conjugation of cysteine residues under catalyst-, additive-, and metal-free conditions.

Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description ejoc202500480-sup-0001-SuppData-S1.pdf4.9 MB Supplementary Material References 1, , , J. Med. Chem. 2014, 57, 10257. 2, , J. Med. Chem. 2011, 54, 3451. 3, RSC Med. Chem. 2020, 11, 745. 4, , , , , , , , Euro. J. Med. Chem. 2015, 102, 487. 5, , , , , , Expert Opini. Drug Discovery 2022, 17, 969. 6, Chem. Rev. 2012, 112, 3641. 7, , , , , , , , , Org. Biomol. Chem. 2015, 13, 4993. 8, , , , , , , , , Tetrahedron Lett.