Arnav Ramnath Chatrathi on Muck Rack

Arnav Ramnath Chatrathi

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Articles

Cardiotoxicity induced by multiple myeloma therapies: mechanistic convergence across proteasome inhibitors, CAR-T, and bispecific antibodies

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By Neeraj K. Saini, Nicolas Palaskas, Arnav Ramnath Chatrathi
| Nature
Abstract Cardiovascular toxicity has emerged as an important obstacle to realizing the complete clinical potential of contemporary therapies for multiple myeloma (MM), including proteasome inhibitors (PIs), chimeric antigen receptor T-cell (CAR-T) therapies, and CD3-engaging bispecific antibodies. Here, we discuss the epidemiology, underlying mechanistic pathways, and emerging strategies for preventing therapy-induced cardiotoxicity in MM.
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