Arne Mide Solbakken on Muck Rack

Arne Mide Solbakken

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Articles

The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer

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By Sebastian Meltzer, Annette Torgunrud, Hanna Abrahamsson, Arne Mide Solbakken
| Nature Verified
Abstract Background In colorectal cancer, the inflamed tumour microenvironment with its angiogenic activities is immune- tolerant and incites progression to liver metastasis. We hypothesised that angiogenic and inflammatory factors in serum samples from patients with non-metastatic rectal cancer could inform on liver metastasis risk. Methods We measured 84 angiogenic and inflammatory markers in serum sampled at the time of diagnosis within the population-based cohort of 122 stage I–III patients.
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