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Articles

Long-range repression by ecdysone receptor on complex enhancers of the insulin receptor gene

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By Arnosti DN, Katie Thompson, Will Suber, Rachel Nicholas
| ncbi.nlm.nih.gov
This is a preprint. It has not yet been peer reviewed by a journal. The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed. Display options Abstract The insulin signaling pathway is evolutionarily conserved throughout metazoans, playing key roles in development, growth, and metabolism. Misregulation of this pathway is associated with a multitude of disease states including diabetes, cancer, and neurodegeneration.
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Retinoblastoma protein activity revealed by CRISPRi study of divergent Rbf1 and Rbf2 paralogs

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By Arnosti DN, Ana-Maria Raicu, Patricia H. Castanheira, Raicu AM
| ncbi.nlm.nih.gov
This is a preprint. It has not yet been peer reviewed by a journal. The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed. Display options Abstract Retinoblastoma tumor suppressor proteins are highly conserved transcriptional corepressors, regulating the key transition from G1 to S phase of the cell cycle.
Open in Who Shared Issue with article?
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