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Aroul Ramadass on Muck Rack

Aroul Ramadass

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Articles

Super-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions

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By Nicolas Bertin, Yiwen Fang, Yufen Goh, Aroul Ramadass
| Nature Verified
We identified super-enhancers using K562 H3K27ac ChIP-Seq data from ENCODE14 following the procedure in Hnisz et al.2 with some variations (A flowchart of the data analysis procedures is shown for reference in Figure S1). Briefly, peaks were called from the ChIP-Seq data and peaks located within some distance from each other were stitched together. Super-enhancers were identified from these stitched peaks.
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