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AS Van Rompuy

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Articles

Single-cell profiling in ovarian germ cell and sex cord-stromal tumours - British Journal of Cancer

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By D. Lambrechts, T. Laga, AS Van Rompuy, T. Van Gorp
| Nature Verified
Abstract The tumour microenvironment of rare ovarian germ cell tumours (OGCT) and sex-cord stromal tumours (SCST) remains unexplored. To better understand their immune and stromal landscape, we constructed a blueprint using single-cell RNA sequencing (scRNA-seq). We performed scRNA-seq of 66, 919 cells from twelve fresh tumour samples: seven adult granulosa cell tumour (aGSCT), one juvenile GSCT (jGSCT), one Sertoli-Leydig (SL) tumour, two immature teratoma (IT) and one dysgerminoma (DG).
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