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Ashinikumar Singh Hidam on Muck Rack

Ashinikumar Singh Hidam

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Articles

Tumor slice cultures enable rapid ex vivo profiling of patient-specific drug sensitivity in pancreatic ductal adenocarcinoma

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By Benedikt Färber, Jannis Duhn, Louisa Bolm, Kim C. Honselmann, Steffen Deichmann, Christoph Röcken, Jens Marquardt, Timo Gemoll, Susanne Sebens, Tobias Keck, Ulrich F. Wellner, Rüdiger Braun Verified, Benjamin Heckelmann, Daniel Fetzner, Olga Lapshyna, Ashinikumar Singh Hidam, Annika Brauer, Anna Maxi Wandmacher, Darko Carstven, Corinna Keber
| Nature Verified
Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterized by chemotherapy resistance, partly driven by its dense and heterogeneous tumor microenvironment (TME). Since most preclinical PDAC models inadequately capture the tissue architecture, their translational value for therapeutic testing remains limited.
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