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Ashley M. Yingst on Muck Rack

Ashley M. Yingst

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Articles

Human innate lymphoid cell precursors express CD48 that modulates ILC differentiation through 2B4 signaling

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By Dejene Tufa, Ashley M. Yingst, George Devon Trahan, Tyler Shank
| Science Magazine Verified
Differentiation distinctions Murine innate lymphoid cell (ILC) differentiation has been studied in detail, but human ILC development is less well understood because of differences in surface markers between species. Tufa et al. show that human common innate lymphoid progenitors (CILPs), characterized as CD34+CD117+α4β7+Lin−, express CD48 and CD52 and can give rise to NK cell progenitors (NKPs) and ILC progenitors.
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