Ashwin Shetty
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Articles by Ashwin Shetty
Motherhood and Albinism: Facts, challenges and strength
Motherhood is a deeply personal and transformative journey, but for women living with albinism, it is often accompanied by unique medical, social, and emotional challenges. Unfortunately, myths and misconceptions about albinism continue to create unnecessary fear, stigma, and discrimination. Greater awareness and understanding can help ensure that women with albinism receive the support, respect, and healthcare they deserve throughout their motherhood journey.
Molecular cues from distinct neuron classes drive differential myelination in the neocortex
Keywords oligodendrocytes projection neurons cell-cell interactions cortical myelination single-cell RNA sequencing Get full text access Log in, subscribe or purchase for full access. References 1. Nave, K.A. ∙ Werner, H.B. Myelination of the nervous system: Mechanisms and functions Annu. Rev. Cell Dev. Biol. 2014; 30:503-533 2. Tomassy, G.S. ∙ Dershowitz, L.B. ∙ Arlotta, P. Diversity Matters: A Revised Guide to Myelination Trends Cell Biol. 2016; 26:135-147 3. Kremer, D. ∙ Göttle, P. ∙ Hartung, H.P. ...
Dimensional Accuracy of Polyether Elastomeric Impression Materials After Using Chitosan as a Disinfectant: A Sustainable Approach to Dental Infection Control
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
World Backup Day Offers a Reminder to Protect your Data Every Day
Last week, someone in my office mentioned that 31st March is celebrated internationally as World Backup Day. Personally, I am not a huge fan of these so-called special days AKA “Valentine’s Day,” “Women’s Day,” “Father’s Day,” “Mother’s Day,” etc. You need to care, love, and treat each other with respect throughout the year rather than wait for a special day to appreciate/recognize someone. Drawing parallels to World Backup Day is easy to do. Backup never takes a break.
Neuronal-class specific molecular cues drive differential myelination in the neocortex
Abstract In the neocortex, oligodendrocytes produce distinct amounts of myelin in each cortical layer and along the axons of individual neuron types. Here we present a comprehensive single-cell molecular map of mouse cortical oligodendrocytes across different cortical layers and stages of myelination, spanning the initiation of cortical myelination into adulthood.
Backup and recovery for Amazon Elastic Block Store (EBS) Volumes and Elastic Cloud Compute (EC2) Instances just got easier
Secure your enterprise workloads: Backup and recovery for Amazon Elastic Block Store (EBS) Volumes and Elastic Cloud Compute (EC2) Instances just got easier Introducing the enhanced HPE Backup and Recovery Service to backup and recover Amazon EBS Volumes and EC2 Instances. Delivered through HPE GreenLake, this service helps to backup and recover Amazon EBS Volumes and EC2 instances across multiple accounts against threats in a simple and cost-efficient approach.
Common and Distinct Disruptions of Cortical Surface Morphology Between Autism Spectrum Disorder Children With and Without SHANK3 Deficiency
Introduction SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) is a master postsynaptic density scaffolding protein that is crucial for synaptogenesis, dendritic spine maturation, and synapse formation (Jiang and Ehlers, 2013; Monteiro and Feng, 2017). Mutations in genes coding for synaptic proteins consist of the most well-characterized genetic deficits reported in autism spectrum disorder (ASD; de la Torre-Ubieta et al., 2016).
Frontiers | Modulation of Dorsolateral Prefrontal Cortex Glutamate/Glutamine Levels Following Repetitive Transcranial Magnetic Stimulation in Young Adults With Autism | Neuroscience
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by complex phenotypic and neurobiological heterogeneity. A number of studies point to the possible convergence of altered excitatory glutamatergic and inhibitory γ-aminobutyric acid (GABA) mediated neurotransmission in ASD (Ford and Crewther, 2016; Ajram et al., 2019).
NextGen HPE StoreOnce Systems Enhance Hybrid Cloud Data Protection
By Ashwin Shetty, product marketing, Hewlett Packard Enterprise Development LP “I love watching superhero movies, and I am happy to report that there is no shortage of superheroes in the movie world today. The concept of superheroes and their alternate fantasy world appeals universally. It is no secret that at some point in our lives, we all – most likely – wanted to be a superhero.
Frontiers | PRG5 Knockout Precipitates Late-Onset Hypersusceptibility to Pilocarpine-Induced Juvenile Seizures by Exacerbating Hippocampal Zinc Signaling-Mediated Mitochondrial Damage | Neuroscience
Introduction Approximately 70 million people worldwide suffer from epilepsy, half of which are children, in whom the prevalence is approximately 0.5–0.8% (Málaga et al., 2019).
Alterations of Regional Homogeneity in Preschool Boys With Autism Spectrum Disorders
Introduction Autism spectrum disorders (ASD) have social disorders, communication difficulties, repetitive and stereotyped behaviors, and limited and narrow interests as the core symptoms. These neurodevelopmental disorders occur early in childhood. The latest large-scale global survey has estimated that the incidence rate of ASD is about 1–2%, and it has been steadily increasing (Lai et al., 2014).
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes
An in vivo analysis of autism risk genes CRISPR targeting in vivo, especially in mammals, can be difficult and time consuming when attempting to determine the effects of a single gene. However, such studies may be required to identify pathological gene variants with effects in specific cells along a developmental trajectory. To study the function of genes implicated in autism spectrum disorders (ASDs), Jin et al.
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with Autism risk genes
New Results View ORCID ProfileXin Jin, Sean K. Simmons, Amy X. Guo, Ashwin S. Shetty, Michelle Ko, Lan Nguyen, Elise Robinson, Paul Oyler, Nathan Curry, Giulio Deangeli, Simona Lodato, View ORCID ProfileJoshua Z. Levin, Aviv Regev, Feng Zhang, Paola Arlotta doi: https://doi.org/10.1101/791525 Abstract The thousands of disease risk genes and loci identified through human genetic studies far outstrip our current capacity to systematically study their functions.
Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits
CHD8 Is Expressed in Most Cell Types throughout the Brain CHD8 Affects Pathways Involved in Cell Cycle and Histone and Chromatin Modification Cortical Lamination, Major Cell Types, and Late-Stage Cortical Progenitor Number in the Somatosensory Cortex Do Not Vary between Chd8+/– and Wild-Type Mice Chd8+/– Mice Exhibit Broad Gene Expression Changes throughout the Brain Chd8+/– Mice Exhibit Synaptic Dysfunction within MSNs in the NAc CHD8 Is Expressed in Most Cell Types throughout the Brain CHD8...
HP Blogs - What are customers saying about HP StoreOnce and d... - The HP Blog Hub
This , it’s Vegas time again! HP Discover 2015 returns next week! With fun, bright lights and lots of sun, you also have the opportunity to witness (live and in person or virtually) how we’re changing the IT landscape with the latest technology innovations. Last week, my social media savvy colleague posted a blog on and other events to add to your agenda.
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