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Aslak E. Lyster on Muck Rack

Aslak E. Lyster

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Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men - Nature Metabolism

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By Christian T. Voldstedlund, Adam Rose, Natalie Krahmer, Christoffer Clemmensen, Erik Richter, Andreas M. Fritzen, Aslak E. Lyster
| Nature Verified
Abstract Dietary protein restriction increases energy expenditure and enhances insulin sensitivity in mice. However, the effects of a eucaloric protein-restricted diet in healthy humans remain unexplored. Here, we show in lean, healthy men that a protein-restricted diet meeting the minimum protein requirements for 5 weeks necessitates an increase in energy intake to uphold body weight, regardless of whether proteins are replaced with fats or carbohydrates.
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