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Articles by Athanasios Chalkias
Haemodynamic effects of selective venoconstriction with centhaquine in spontaneously breathing patients with mixed hypovolaemic-vasodilatory shock
1 INTRODUCTION Combined shock is a life-threatening condition defined by the coexistence of a primary shock state with one or more additional pathophysiological components (Gaieski & Mikkelsen, 2025). Among its variants, mixed hypovolaemic–vasodilatory shock (MHVS) represents a particularly complex and clinically relevant phenotype frequently encountered in perioperative, emergency and critical care settings.
On the Intensity of the Microvascular Magnetic Field in Normal State and Septic Shock
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Characterization of Sublingual Microvascular Tortuosity in Steady-State Physiology and Septic Shock
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Characterization of Sublingual Microvascular Tortuosity in Steady-State Physiology and Septic Shock
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IJMS | Free Full-Text | Effect of Centhaquine on the Coagulation Cascade in Normal State and Uncontrolled Hemorrhage: A Multiphase Study Combining Ex Vivo and In Vivo Experiments in Different Species
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
IJMS | Free Full-Text | Shear Stress and Endothelial Mechanotransduction in Trauma Patients with Hemorrhagic Shock: Hidden Coagulopathy Pathways and Novel Therapeutic Strategies
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Athanasios Chalkias 1,2 1 Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-5158, USA 2 Outcomes Research Consortium, Cleveland, OH 44195, USA Int. J. Mol. Sci.
JPM | Free Full-Text | A Hypertonic Seawater Nasal Irrigation Solution Containing Algal and Herbal Natural Ingredients Reduces Viral Load and SARS-CoV-2 Detection Time in the Nasal Cavity
Open AccessArticle by Ioannis Pantazopoulos 1,2,*, Athanasios Chalkias 3,4,5, Angeliki Miziou 2, Michalis Spanos 1, Efrosyni Gerovasileiou 2, Erasmia Rouka 6 and Konstantinos Gourgoulianis 2 1 Department of Emergency Medicine, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece 2 Department of Respiratory Medicine, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece 3 Department of Anaesthesiology, Faculty of Medicine, University of Thessaly, 41500 Larissa,...
General Critical Care, Temperature Control, and End-of-Life Decision Making in Patients Resuscitated from Cardiac Arrest
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Athanasios Chalkias 1,2,*, Georgios Adamos 3 and Spyros D.
Transfusion increased skin blood flow when initially low in volume-resuscitated patients without acute bleeding
Elaine Cavalcante dos Santos* Péter Bakos Diego Orbegozo Jacques Creteur Jean-Louis Vincent Fabio Silvio Taccone Department of Intensive Care Medecine, Erasme University Hospital, Université Libre de Bruxelles (ULB), Brussels, Belgium Background: Alterations in skin blood flow is a marker of inadequate tissue perfusion in critically ill patients after initial resuscitation. The effects of red blood cell transfusions (RBCT) on skin perfusion are not described in this setting.
A critical appraisal of the effects of anesthetics on immune system modulation in critically ill patients with COVID-19
This paper is only available as a PDF. To read, Please Download here. Abstract Purpose The aim of the present article is to briefly summarize current knowledge about the immunomodulatory effects of general anesthetics and the possible clinical effects of this immunomodulation in patients with COVID-19. Methods The PubMed, Scopus, and Google Scholar databases were comprehensively searched for relevant studies.
Development and testing of a novel anesthesia induction/ventilation protocol for patients with cardiogenic shock complicating acute myocardial infarction
Publication HistoryPublished online: April 20, 2018Accepted: April 15, 2018; Received in revised form: April 14, 2018; Received: December 9, 2017;
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