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Atreyi Dasgupta

As seen in: Texas Medical Center
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Articles

Modeling Ewing Sarcoma Lung Metastasis

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By Atreyi Dasgupta, Lyazat Kurenbekova, Tajhal D Patel, Kimal Rajapakshe
| Texas Medical Center
Ewing Sarcoma (EwS) is the second most common malignant bone tumor in adolescents and young adults. The single-most powerful predictor of outcome in EwS is presence of metastatic burden at the time of diagnosis. Patients with metastatic Ewing Sarcoma have an abysmal 5-year survival rate of 10–25%, which has not changed over the past 30–40 years. Thus, unraveling underlying mechanisms of EwS metastasis are imperative for developing effective therapeutic measures.
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Targeting PAK4 Inhibits Ras-Mediated Signaling and Multiple Oncogenic Pathways in High-Risk Rhabdomyosarcoma

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By Atreyi Dasgupta, Laura Sierra Verified, Susan V. Tsang, Lyazat Kurenbekova
| cancerres.aacrjournals.org
Translational Science Atreyi Dasgupta, Laura Sierra, Susan V. Tsang, Lyazat Kurenbekova, Tajhal Patel, Kimal Rajapakse, Ryan L. Shuck, Nino Rainusso, Yosef Landesman, Thaddeus Unger, Cristian Coarfa and Jason T. Yustein DOI: 10.1158/0008-5472.CAN-20-0854 Published January 2021 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below.
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Targeting PAK4 inhibits Ras-mediated signaling and multiple oncogenic pathways in high-risk Rhabdomyosarcoma

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By Laura Sierra Verified, Lyazat Kurenbekova, Atreyi Dasgupta, Susan V. Tsang
| cancerres.aacrjournals.org
Research Article Atreyi Dasgupta, Laura Sierra, Susan V. Tsang, Lyazat Kurenbekova, Tajhal Patel, Kimal Rajapakshe, Ryan L. Shuck, Nino Rainusso, Yosef Landesman, Thaddeus Unger, Cristian Coarfa and Jason T. Yustein DOI: 10.1158/0008-5472.CAN-20-0854 Abstract Rhabdomyosarcoma (RMS) is the most prevalent pediatric soft tissue sarcoma. Multimodal treatment including surgery and traditional chemotherapy with radiotherapy have contributed to improvements in overall survival rates.
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