Skip To Main Content
Atrin Dizehchi on Muck Rack

Atrin Dizehchi

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Atrin

Contact Atrin, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Predictive design of tissue-specific mammalian enhancers that function in the mouse embryo

|
By Vincent LOUBIERE, Ethan Hollingsworth, Ken Murakami, Sandra Jacinto, Jacob Schreiber, Evgeny Kvon, Alexander Stark, Shenzhi Chen, Nikolaus Mandlburger, Atrin Dizehchi
| Nature Verified
Abstract Enhancers control tissue-specific gene expression across animals1. Although deep learning2,3 has enabled enhancer prediction and design in mammalian cell lines and non-mammalian model organisms4,5,6,7,8,9,10 (reviewed in a previous publication11), it remains unclear whether such approaches can operate within the regulatory complexity of mammalian genomes and tissues in vivo. Here we present a general strategy for designing tissue-specific enhancers that function reliably in mice.
Open in Who Shared Issue with article?
See all 1 articles