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Aurimantas Pelanis on Muck Rack

Aurimantas Pelanis

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Articles

Divergence of C4A and C4B in first-episode psychosis: Insights from CSF and plasma immune profiling

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By Shokouh Arjmand, Mridul Chaudhary, Fredrik Piehl, Göran Engberg, Simon Cervenka, Mikael Landén, Sophie Erhardt, Carl M. Sellgren, Aurimantas Pelanis
| Nature Verified
Abstract The complement genes C4A and C4B share high sequence similarity yet differ in biological function and disease relevance. C4A, in contrast to C4B, is implicated in synaptic pruning and increased risk for schizophrenia, however beyond this their distinct roles within the human brain remain poorly understood.
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