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Avi Sura on Muck Rack

Avi Sura

As seen in: BioRxiv
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Articles

Brain Specific Estrogen Ameliorates Cognitive Effects of Surgical Menopause in Mice

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By Abigail E. Salinero, Charly Abi-Ghanem, Harini Venkataganesh, Avi Sura
| BioRxiv
Abstract Menopause is a major endocrinological shift that leads to an increased vulnerability to the risk factors for cognitive impairment and dementia. This is thought to be due to the loss of circulating estrogens, which exert many potent neuroprotective effects in the brain. Systemic replacement of estrogen post-menopause has many limitations, including increased risk for estrogen-sensitive cancers.
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