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Avijay Sen on Muck Rack

Avijay Sen

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Articles

Near-atomic in situ architecture and membrane-coupled dynamics of the Vibrio cholerae sheathed flagellum

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By Wangbiao Guo, Jian Yue, Jin Hwan Park, Diana Valverde-Mendez, Jack M. Botting, Huaxin Yu, Rajeev Kumar, Jing Yan, Fitnat H Yildiz, Jun Liu, Avijay Sen
| Nature Verified
Abstract The sheathed flagellum of Vibrio cholerae is a self-assembling membranous organelle that coordinates flagellar assembly, sheath biogenesis, and rapid rotation. Here, we determine in-situ near-atomic structures of the sheathed flagellar motor within intact cells. The motor anchors to the outer membrane through lipidated HL-rings without forming a membrane pore, thereby enabling flagellar assembly to drive sheath formation.
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