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Articles

A Chirality-Guided Molecular Recognition Strategy for Targeting Intrinsically Disordered Proteins

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By Kenta Morita, ayaka hayashi, Shiho Seguchi
| Wiley Online Library Verified
Kenta Morita and Shiho Seguchi contributed equally. K.Morita, S.Seguchi, A.Hayashi, et al. “A Chirality-Guided Molecular Recognition Strategy for Targeting Intrinsically Disordered Proteins.” Chemistry – A European Journal (2026): e70889. https://doi.org/10.1002/chem.70889 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
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Oxidation-guided and collision-induced linearization assists de novo sequencing of thioether macrocyclic peptides

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By ayaka hayashi, Yuki Goto, Yutaro Saito, Hiroaki Suga
| Royal Society of Chemistry Verified
Oxidation-guided and collision-induced linearization assists de novo sequencing of thioether macrocyclic peptides Oxidation of a thioether linkage in thioether-closed macrocyclic peptides led to collision-induced site-selective linearization of the peptides. This method has allowed for de novo sequencing of thioether macrocyclic peptides.
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