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Ayelet-Hashahar Orenbuch on Muck Rack

Ayelet-Hashahar Orenbuch

As seen in: Nature
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Articles

Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming

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By Irina Miodownik, Yoav Mayshar, Raz Ben-Yair, Hernan Rubinstein, Aviezer Lifshitz, Alexander Wainstein, Daoud Sheban, Liran Shlush, Amos Tanay, Ariel Afek, Yonatan Stelzer, Arik Toren, Liron Hoffman, Ayelet-Hashahar Orenbuch, Roni Stok Ranen
| Nature Verified
Abstract Genomic imprinting secures parent-specific gene expression through differential DNA methylation at imprinted control regions (ICRs). However, how unmethylated alleles resist de novo methylation remains unclear.
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