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Ayla Debraekeleer on Muck Rack

Ayla Debraekeleer

As seen in: Nature, Future Medicine
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Articles

Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq

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By Lize Allonsius, Eva Hadadi, Daliya Kancheva, Morgane Paque, Ayla Debraekeleer, Ria Roelandt, Kevin Verstaen, Delphine Hoton, Louis Boon, Arnaud Blomme, Sofie Deschoemaeker, Geert Raes, Elly Marcq, Jan P. Böttcher, Jitka Fucikova, Pierre Close, Frank Aboubakar Nana, Damya Laoui, Pauline M. R. Bardet, Sarka Vosahlikova, Aarushi A. Caro, Anouk Van Audenhove, Michal Hensler, Gisèle Mateu Cabrera, Ahmed E. I. Hamouda
| Nature Verified
Abstract Relevant pre-clinical models are essential for driving progress in cancer therapy research. Here, we develop a pre-clinical study framework using an injectable orthotopic lung adenocarcinoma (LUAD) model (ORTHO) that replicates key features of human LUAD patients and is dissectible into tumoural and non-tumoural adjacent tissue, in analogy with patient samples.
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Future perspective for potential Helicobacter pylori eradication therapies

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By Han Remaut, Gaetano Ivan Dellino, Pier Giuseppe Pelicci, Ayla Debraekeleer
| Future Medicine Verified
This work was supported by the FWO Flanders through grant G033717N. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.
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