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Study of novel pro-viral activities of non-structural protein 1 (NS1) of influenza A virus
English The non-structural protein 1 (NS1) of influenza A virus performs a broad variety of proviral activities in the infected cell, primarily mediating evasion from the host innate immune response by being the main viral interferon antagonist. However, among the multiple interactions described for this small multifunctional protein, there are several whose biological relevance remains obscure, such as the ability of NS1 to bind and activate class IA phosphoinositide 3kinases (PI3Ks).
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