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Articles by Ayman Grada
Dual site targeting of the bacterial 70S ribosome by tetracyclines
Abstract The tetracycline class of antibiotics is widely used for treating bacterial diseases including Lyme disease, anthrax, acne vulgaris, and pneumonia. Using a series of high-resolution cryo-electron microscopy (cryo-EM) structures, we show that tetracyclines can simultaneously target the mRNA decoding center in the 30S subunit and the nascent peptide exit tunnel (NPET) in the 50S subunit of the bacterial ribosome.
The interferon paradox in actinic keratosis
Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA Publication History: Published online February 14, 2026 DOI: 10.1016/j.jid.2025.12.027 External LinkAlso available on ScienceDirect External Link Copyright: © 2026 Society for Investigative Dermatology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
Seborrheic Dermatitis in the United States: Stable National Rates With Marked State‐Level Variation, 2010-2021
No abstract is available for this article. Conflicts of Interest A.G. is an unpaid official Senior Collaborator for IHME/GBD. He serves as an Associate Editor for the Journal of Investigative Dermatology and the International Journal of Dermatology, a Physician Editor for VisualDx, a member of the Board of Directors for the Biology of Skin Foundation, and a Medical Director at AbbVie.
Outpatient Cutaneous Wound Care in the United States: Specialty Distribution and Antimicrobial Prescribing Patterns
Submitted: 07 December 2025 You are already at the latest version Background: Cutaneous wounds are common in outpatient care, but national patterns of who manages them and how antimicrobials are used remain unclear. Objectives: To characterize outpatient specialty involvement and antimicrobial use for acute and chronic cutaneous wound visits in the United States. Methods: We conducted a retrospective cross-sectional analysis of 2011–2019 National Ambulatory Medical Care Survey (NAMCS) data.
Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease
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Oral Tetracycline-Class Drugs in Dermatology: Impact of Food Intake on Absorption and Efficacy
Abstract : Tetracycline-class drugs are frequently used in dermatology for their anti-inflammatory properties to treat skin diseases such as acne, rosacea, and hidradenitis suppurativa (HS). The American Academy of Dermatology (AAD) clinical guidelines do not offer guidance regarding the co-administration of food with tetracycline-class drugs.
Demystifying Hand Eczema
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Prescribing Trends for Acne Vulgaris Visits in the United States
Abstract : Acne vulgaris is the most common reason for pediatric patients and third most common reason for adult patients to seek care from a dermatologist in the US. However, referring providers may be reluctant to initiate patients on acne treatment or certain prescriptions. We assessed over-the-counter (OTC) and prescription acne (antibiotic and non-antibiotic) treatment rates to characterize differences by patient demographics and provider specialty.
Marked Truncal Acne Response to Sarecycline Monotherapy in Different Ethnicities
Main Article Content Angela Moore Arlington Research Center, Arlington, TX, USA Stephen Moore Arlington Research Center, Arlington, TX, USA Luke Moore Arlington Research Center, Arlington, TX, USA Ayman Grada Baylor University Medical Center, Dallas, TX Stephen Tyring UT Health McGovern Medical School, Houston, TX, USA Keywords acne Abstract N/A References 1. Del Rosso JQ, Stein-Gold L, Lynde C, Tanghetti E, Alexis AF. Truncal Acne: A Neglected Entity. J Drugs Dermatol. 2019;18(12):205-1208. 2.
Efficacy and Safety of Narrow-spectrum Oral Sarecycline for Moderate to Severe Acne Vulgaris
Main Article Content Angela Moore Baylor University Medical Center, Dallas, Texas, USA; Arlington Research Center, Arlington, Texas, USA Lawrence J. Green Lawrence J. Green, MD, LLC, George Washington University School of Medicine, Washington, DC, USA Jodi L.
Immune-Mediated and Psychiatric Comorbidities Among Patients Newly Diagnosed With Alopecia Areata
Ayuda Buscar en la ayuda Buscar en la ayuda Immune-Mediated and Psychiatric Comorbidities Among Patients Newly Diagnosed With Alopecia Areata Autores: M Arash Mostaghimi, Ahmed M. Soliman, Chao Li, Yazan K. Barqawi, Ayman Grada Localización: JAMA Dermatology, ISSN 2168-6068, Vol. 160, Nº. 9, 2024, págs.
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