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Ayse Ceren Mutgan on Muck Rack

Ayse Ceren Mutgan

As seen in: American Journal of Physiology
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Articles

Pentastatin, a matrikine of the collagen IVα5, is a novel endogenous mediator of pulmonary endothelial dysfunction

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By Katharina Jandl, Ayse Ceren Mutgan, Nemanja Radic, Francesco Valzano
| American Journal of Physiology Verified
The basement membrane (BM) has increasingly emerged as an important determinant of endothelial cell (EC) function, thereby contributing to pulmonary vascular diseases such as pulmonary hypertension (PH) (1). The BM consists of a set of extracellular matrix (ECM) proteins, mainly type IV collagens, laminins, and proteoglycans such as perlecan and collagen XVIIIα1 (ColXVIIIα1) (2, 3).
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