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Abstract Colorectal cancer (CRC) is a leading cause of cancer-related mortality globally, necessitating biomarkers for early detection and targeted therapies. We integrated RNA-seq (GSE180440) weighted gene co-expression analysis with experimental validation to identify coding and long non-coding RNA biomarkers associated with tumor biology and treatment response.
Abstract Background Esophageal cancer is one of the most common malignancies among Iranians and is categorized as adenocarcinoma and squamous cell carcinoma. Various environmental and genetic factors are involved in this malignancy. Despite the recent advances in therapeutic modalities there is still a noticeable mortality rate among such patients which can be related to the late diagnosis.
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