Diagnostic Pathology

Verified
Journal, Online/Digital
Diagnostic Pathology is an open access, peer-reviewed, online journal that considers research in surgical and clinical pathology, immunology, and biology, with a special focus on cutting-edge approaches in diagnostic pathology and tissue-based therapy. The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis-related diagnosis (tumor stages, prognosis markers, such as MIB-percentage, hormone receptors, etc.), and therapy-related findings. The journal also focuses on the technological aspects of pathology, including molecular biology techniques, morphometry aspects (stereology, DNA analysis, syntactic structure analysis), communication aspects (telecommunication, virtual microscopy, virtual pathology institutions, etc.), and electronic education and quality assurance (for example interactive publication, on-line references with automated updating, etc.). Source

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Scope National, Trade/B2B
Language English
Country United States of America
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Prognostic value of manual and digital PD-L1 expression in pT3 and pT4 colon cancer - Diagnostic Pathology

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By Trine Lønbo Grantzau, Dea Natalie Munch, Jens Ole Eriksen, Marianne Bøgevang, Astrid Louise Bjørn, Trine Lønbo, Michael Bzorek, Ismail Gögenur, Anne-Marie Fiehn, Marianne Bøgevang Jensen, Thomas Thiilmark Eriksen
| Diagnostic Pathology Verified
References Jiang X, Zhan Y, Yang D-H, Bao L. Immunotherapy in gastrointestinal cancers: current insights. Clin Pharmacol. 2025;17:167–83. Google Scholar Lin X, Kang K, Chen P, Zeng Z, Li G, Xiong W, et al. Regulatory mechanisms of PD-1/PD-L1 in cancers. Mol Cancer. 2024;23:108. Google Scholar Akhtar M, Rashid S, Al-Bozom IA. PD-L1 immunostaining: what pathologists need to know. Diagn Pathol. 2021;16:94. Google Scholar Chen X, Chen L-J, Peng X-F, Deng L, Wang Y, Li J-J, et al.
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Prognostic utility of macrophage polarization (CD68/CD163 ratio) in Egyptian JAK2 positive myeloproliferative neoplasm patients: a single center study | Diagnostic Pathology | Full Text

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By Marwa Mohamed, Shirihan Mahmoud Anwar, Aya Mohammed Adel
| Diagnostic Pathology Verified
The study methodology received endorsement from the institutional research and ethics council of Kasr Al-Ainy Cairo University (Code N-34–2025). In this retrospective cohort, a total of one hundred and twenty-one patients with histopathologically proven MPNs evaluated for the macrophage markers expression (CD163 and CD68) in trephine BMB attended the Hematology Department, Kasr A-Ainy School, Cairo University, during the period between January 2019 and January 2024.
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Molecular abnormalities and clinical features in adult patients with acute myeloid leukemia in Thailand - Diagnostic Pathology

| Diagnostic Pathology Verified
References Murati A, Brecqueville M, Devillier R, Mozziconacci MJ, Gelsi-Boyer V, Birnbaum D. Myeloid malignancies :mutations, models and management. BMC Cancer. 2012;12:304. https://doi.org/10.1186/1471-2407-12-304. Article CAS PubMed PubMed Central Google Scholar Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129:424–47.
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Histopathological profile of endometrium among peri and post-menopausal women with abnormal uterine bleeding and its correlation with endometrial thickness by transvaginal sonography: a retrospective study | Diagnostic Pathology | Full Text

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By Manipal Academy
| Diagnostic Pathology Verified
The study analysed a total of 307 cases of abnormal uterine bleeding (AUB) in women aged 40 years and above. Among these, 79.2% were categorized as perimenopausal, 19.5% as postmenopausal based on menstrual history. Menopause status was not known in 1.3% cases. Menorrhagia was the most common symptom, followed by postmenopausal bleeding and dysmenorrhea. Flow diagram of histomorphology Endometrial sampling was obtained by curettage and biopsy.
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Clinical significance of quantification of perineural cancer invasion on MRI-targeted prostate biopsy - Diagnostic Pathology

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By Madhurya Ramineni, Ying Wang, Hiroshi Miyamoto
| Diagnostic Pathology Verified
References Torre LA, Bray F, Siegel RL, Ferlay J, Loretet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87–108. PubMed Google Scholar Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistic 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229–63. Google Scholar Lancee M, Tikkinen KAO, de Reijke TM, Kataja VV, Aben KKH, Vernooij RWM.
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Integrated in-silico and in-vitro analysis of lncRNA H19/miRNA-675/p53 in OSCC: Structural characterization and molecular docking insights - Diagnostic Pathology

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By Meenakshi Academy, Tamil Nadu, Ramya Sekar, Selvaraj Jayaraman, Vishnupriya Veeraraghavan, Saranya Varadarajan, Manikandan Alagumuthu, Peramaiyan Rajendran, Bargavi Venkatesalu
| Diagnostic Pathology Verified
This study employed an integrative approach combining in-silico and in-vitro analyses to investigate the relationship between lncRNA H19, miRNA-675, and p53 in patients with OSCC compared to healthy individuals. The study protocol was approved by the Institutional Human Ethical Committee (IHEC/SDC/PHD/BIOCHEM-2108/21/TH-035(B)). The secondary structure of lncRNA H19 was predicted using the RNAfold web server (http://rna.tbi.univie.ac.at/cgi-bin/RNAWebSuite/RNAfold.cgi) [24].
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High-grade uterine endometrial stromal sarcoma harboring GLI1 and MDM2/CDK4 co-amplifications - Diagnostic Pathology

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By Lili Zhang, Lijuan Luan, Lei Zhang, Yufeng Huang, Wenyi Gu, Shui Yu, Licheng Shen, Jie Huang, Yang Shao, Jieakesu Su, Yingyong Hou, Chen Xu
| Diagnostic Pathology Verified
This retrospective study was performed with the approval of Zhongshan Hospital, Fudan University review board. The pathology files were searched for endometrial stromal sarcomas (ESS) of surgical specimens in female patients from January 2016 to August 2022 including inpatient pathology and consultation pathology records. A total of 31 cases of ESS (20 LGESS and 11 HGESS), 1 uterine adenosarcoma (sarcoma component is HGESS) were included.
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Diagnostic value of AHNAK2 immunohistochemical expression in papillary thyroid carcinoma: an immunohistochemical study - Diagnostic Pathology

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By Xinyi Zhang, Lingli Chen, Minying Deng, Huaiyu Liang, Dongxian Jiang, Huimei Wang, Yufeng Liu, Rui Zhang, Lei Xu, Jia Liu, Chen Xu, Yalan Liu, Yingyong Hou, Akesu Sujie
| Diagnostic Pathology Verified
A total of 463 thyroid neoplasm patients, including 296 PTC patients, 36 FTC patients, 11 NIFTP patients, and 167 FA patients, were recruited from January 2018 to December 2022 in the Pathology Department of Zhongshan Hospital, Fudan University. All patients underwent total thyroidectomy or unilateral thyroidectomy with isthmic thyroidectomy, followed by histopathological diagnosis. Ethical approval was obtained from the ethics committee of Zhongshan Hospital, Fudan University (B2024-169).
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Inflammatory fibroid polyps of the colon: a study on the morphological spectrum, immunoexpression characteristics, and outcomes - Diagnostic Pathology

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By Qin Changfei, Zhang Tingzhen, Lin Xiangling, Liao Dingzhun, Wen Zhang
| Diagnostic Pathology Verified
References Vanek J. Gastric submucosal granuloma with eosinophilic infiltration. Am J Pathol. 1949;25(3):397–411. CAS PubMed PubMed Central Google Scholar Helwig EB, Ranier A. Inflammatory fibroid polyps of the stomach. Surg Gynecol Obstet. 1953;96(3):335–67. CAS PubMed Google Scholar Schildhaus HU, Merkelbach-Bruse S, Binot E, Büttner R, Wardelmann E. [Inflammatory fibroid polyp: from vanek’s submucosal granuloma to the concept of submucosal mesenchymal neoplasia]. Pathologe. 2010;31(2):109–14.
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Two unusual cases of tongue schwannoma with self-injurious factors: case reports and systemic literature review - Diagnostic Pathology

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By Gefei Du, Jiali Zhang, Xinming Chen, Rui Lu, Enno Schmidt, Gang Zhou
| Diagnostic Pathology Verified
References Asadi M, Mohseni M, Jahanshahi F, Esmaeili A, Mohsenifar Z. Schwannoma (neurilemmoma) of tongue: A rare case presentation and review of literature. Clin Case Rep. 2023;11(4):e7235. Article PubMed PubMed Central Google Scholar Di Pascuale I, Brito N, Zerpa J, Roa C, Faria G. Hypoglossal nerve schwannoma: case report and literature review. World Neurosurg. 2020;135:205–08. Article PubMed Google Scholar Lee EY, Kim JJ, Seok H, Lee JY.
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Diagnostic Pathology Journalists

Parwani, Anil