Baback Roshanravan

Abstract Facioscapulohumeral muscular dystrophy (FSHD) is caused by epigenetic dysregulation of the disease locus, leading to pathogenic misexpression of DUX4 in skeletal muscle. Thus, most FSHD therapeutic approaches target DUX4. Our previous study identified the chromatin remodeling factor BAZ1A (bromodomain adjacent to zinc finger domain protein 1A) as a promising target for therapeutic development.

Painter P. Roshanravan B. The association of physical activity and physical function with clinical outcomes in adults with chronic kidney disease. Curr Opin Nephrol Hypertens. 2013; 22: 615-623 Porter A. Fischer M.J. Wang X. et al. Quality of life and outcomes in African Americans with CKD. J Am Soc Nephrol. 2014; 25: 1849-1855 Roshanravan B. Robinson-Cohen C. Patel K.V. et al. Association between physical performance and all-cause mortality in CKD. J Am Soc Nephrol. 2013; 24: 822-830 Roshanravan B. Khatri M.