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Articles by Badong Chen
Brain contrastive modeling reveals depression subtypes with distinct treatment response and progression
Abstract Major Depressive Disorder (MDD) is highly heterogeneous, limiting treatment efficacy. Despite efforts to delineate patient heterogeneity through subtyping, current approaches remain limited by noise, lack of clinical applicability, and insufficient external validation. Crucially, they focus on subtyping while neglecting staging information (e.g., illness duration). We developed BrainCVAE, a contrastive variational autoencoder, to disentangle MDD-specific neural features.
Efficient training of neuromorphic electronics
Abstract Neuromorphic electronics can provide in-memory computing systems with low power consumption by emulating key principles of the brain. However, their practical capabilities are limited by a number of challenges, including device non-ideality, limited training accuracy and insufficient adaptability. Here we explore the development of training approaches for neuromorphic electronics, including digital, mixed-signal and emerging neuromorphic electronics.
CI-GNN: A Granger Causality-Inspired Graph Neural Network for Interpretable Brain Network-Based Psychiatric Diagnosis
[Submitted on 4 Jan 2023 ( v1 ), last revised 28 Jan 2024 (this version, v3)] Title:CI-GNN: A Granger Causality-Inspired Graph Neural Network for Interpretable Brain Network-Based Psychiatric Diagnosis Download a PDF of the paper titled CI-GNN: A Granger Causality-Inspired Graph Neural Network for Interpretable Brain Network-Based Psychiatric Diagnosis, by Kaizhong Zheng and 2 other authors Download PDF HTML (experimental) Abstract:There is a recent trend to leverage the power of graph neural...
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