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Bae-Geun Nam on Muck Rack

Bae-Geun Nam

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Articles

Topical application of Cas9 ribonucleoproteins inhibits corneal neovascularization in a mouse model of alkali burn injury

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By Seok Jae Lee, Sung-Ah Hong, Dong Hyun Jo, Sang-Mok Lee, Sangsu Bae, Jeong Hun Kim, Bae-Geun Nam
| Nature Verified
Abstract Corneal neovascularization is a sight-threatening condition for which current treatments such as anti-VEGF agents are limited by invasiveness and side effects. We present the first non-viral, CRISPR/Cas9-based gene therapy delivered via topical eye drops that penetrates the cornea and inhibits pathological neovascularization.
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