Bahaar Chawla on Muck Rack

Bahaar Chawla

As seen in: MDPI
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Articles

Condensin IDC has a Functional ATPase That is Required for X-Chromosome Dosage Compensation in C. elegans

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By Bahaar Chawla, Dillon Sloan, Györgyi Csankovszki, Suchi Jatia
| biorxiv.org
Abstract Dosage compensation (DC) in C. elegans utilizes a condensin complex that resembles mitotic condensins, but differs by one subunit, DPY-27. DPY-27 replaces SMC-4, one of the Structural Maintenance of Chromosome (SMC) proteins that is responsible for hydrolyzing ATP, required for condensation of DNA and other mitotic condensin functions. To understand if the ATPase function is required in DC, we first demonstrated that DPY-27 is capable of hydrolyzing ATP in vitro.
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DNA | Free Full-Text | How Chromatin Motor Complexes Influence the Nuclear Architecture: A Review of Chromatin Organization, Cohesins, and Condensins with a Focus on C. elegans

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By Györgyi Csankovszki, Development. Basque Research, Bahaar Chawla
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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