Baldeep Khare on Muck Rack

Baldeep Khare

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Articles

In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism - Nature Communications

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By Andrei Fokine, Jingen Zhu, Thomas Klose, Frank S Vago, Charles-Adrien Arnaud, Zhiqing Wang, Baldeep Khare, Michael Rossmann, Zhenguo Chen, Lei Sun, Qianglin Fang, Richard Kuhn, Venigalla Rao
| Nature Verified
Abstract The post-genome packaging mechanisms that govern the assembly of an infectious virion are poorly understood in bacteriophages and other viruses. Here, our near-atomic resolution cryo-EM structural analyses uncovered an assembly- and conformation-driven genome positioning mechanism in the tailed bacteriophage T4.
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