Bang Yeon Hwang

Abstract The need for preclinical models that better reflect human substance use patterns has increased due to the rising misuse of electronic cigarettes (e-cigarettes) for drug inhalation. However, Self administration studies using mice in this context remain limited. To address this, we developed a self-administration model in which mice voluntarily insert their nose into a nose poke port, where vaporized cocaine passes through an airway, allowing controlled inhalation.