Bangke Zhang on Muck Rack

Bangke Zhang

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Articles

PRMT6 is required for initiating and amplifying macrophage-induced inflammation in heterotopic ossification by increasing CCL2 expression

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By Wenxiang Chu, Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Liang Wang, Haibin Wang, Chaofeng Han, Xuhua Lu, Bangke Zhang
| Nature Verified
Abstract Heterotopic ossification (HO) is a debilitating disorder marked by ectopic bone formation in soft tissues, frequently triggered by inflammation after trauma. While macrophage-driven inflammation plays a critical role in HO pathogenesis, the molecular mechanisms governing its initiation, amplification and resolution remain elusive.
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