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Banumathi K. Cole

As seen in: PLOS ONE
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Articles

Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk

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By Ryan E. Feaver, M. Scott Bowers, Banumathi K. Cole, Steve Hoàng
| paperity.org
PLOS ONE, Sep 2023 Some health concerns are often not identified until late into clinical development of drugs, which can place participants and patients at significant risk. For example, the United States Food and Drug Administration (FDA) labeled the xanthine oxidase inhibitor febuxostat with a”boxed” warning regarding an increased risk of cardiovascular death, and this safety risk was only identified during Phase 3b clinical trials after its approval.
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Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk

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By HemoShear Therapeutics, M. Scott Bowers, Ryan E. Feaver, Banumathi K. Cole
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Feaver RE, Bowers MS, Cole BK, Hoang S, Lawson MJ, Taylor J, et al. (2023) Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk. PLoS ONE 18(9): e0291330. https://doi.org/10.1371/journal.pone.0291330 Editor: Ahmed E. Abdel Moneim, Helwan University, EGYPT Received: May 5, 2023; Accepted: August 27, 2023; Published: September 8, 2023 Copyright: © 2023 Feaver et al.
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