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Bao Li Zheng

As seen in: Frontiers in Immunology
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Articles

Mechanistic insights into ferroptosis and its therapeutic potential in hepatocellular carcinoma

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By Fan Yang, Zhongjie Li, Bao Li Zheng
| Frontiers in Immunology
Abstract Ferroptosis is an iron-dependent form of programmed cell death driven by lipid peroxidation, distinct from apoptosis and necrosis. It has been confirmed as a key regulator in hepatocellular carcinoma (HCC). This study systematically elucidates three interconnected regulatory networks of ferroptosis—metabolic, epigenetic, and microenvironmental—and proposes a closed-loop regulatory model integrating these dimensions.
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Numerical Investigation of Mechanisms Affecting Performance of Cyclically Loaded Tension Piles in Sand

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By Bao Li Zheng, Bruce L. Kutter
| ascelibrary.org
Abstract Offshore wind turbines supported on jacket structures are subject to many cycles of axial loading due to wind and waves, which may densify the soil around the piles and decrease the lateral stress on the soil-pile interface. Static axial loads may cause dilation of adjacent soil and increase the lateral stress.
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