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Baraa Sakee on Muck Rack

Baraa Sakee

As seen in: Dove Medical Press
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Articles

The Association of Fetal and Maternal Thrombospondin-1 (TSP-1) and Vas

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By Rawan Obeidat, Shereen Hamadneh, Shahd Alguzo, Baraa Sakee
| Dove Medical Press
Background Thrombospondin-1 (TSP-1) and vascular endothelial growth factor (VEGF) are glycoproteins expressed in human trophoblasts and the placenta, playing essential roles in angiogenesis and vascular regulation during pregnancy.1,2 TSP-1, primarily secreted by endothelial cells and activated platelets, exerts anti-angiogenic, pro-thrombotic, and pro-inflammatory effects.
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