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Barak Blum on Muck Rack

Barak Blum

As seen in: Nature, Frontiers
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Articles

The RNA-binding protein CPEB1 marks healthy adult β cells in mice but is dispensable for β cell identity and function - Scientific Reports

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By Barak Blum
| Nature Verified
Abstract RNA binding proteins (RBPs) are increasingly being recognized as important regulators of pancreatic β cells’ identity and function. We identified the poly-A binding RBP, CPEB1, as a potential new regulator linked to β cell failure in diabetes based on its enrichment in mature, healthy adult β cells and its sharp decrease in β cells in type 1 diabetes (T1D) and type 2 diabetes (T2D).
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PyCreas: a tool for quantification of localization and distribution of endocrine cell types in the islets of Langerhans

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By Asuaje Pfeifer, Ingo Burtscher, Barak Blum
| Frontiers
1 Introduction Islets of Langerhans have a complex architecture composed of different endocrine cell types that differ in species such as humans and rodents. Rodent islets are characterized by a well-defined structure consisting of a central core of beta cells surrounded by alpha and delta cells in a mantle-like pattern (1, 2). Endocrine cells in islets of human embryos exhibit a distribution pattern similar to that of adult mice (3, 4).
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