Barat Gal-Er

1 Introduction Congenital heart disease (CHD) is the most prevalent congenital defect, comprising structural abnormalities of the heart and great vessels [1]. Neonates with CHD are at increased risk of altered brain development and impaired neurodevelopmental outcome [2-4], which remain common despite substantial improvements in surgical and perioperative care [5].

Abstract Children with congenital heart disease (CHD) are at increased risk of altered early brain development and neurodevelopmental impairments. Although environmental factors are known to influence neurodevelopmental outcomes, the interplay between neonatal brain structure and the home environment in shaping behavioural outcomes remains unclear.

Abstract Purpose: To validate a retrospective motion correction technique, Distributed and Incoherent Sample Orders for Reconstruction Deblurring using Encoding Redundancy (DISORDER), for pediatric brain morphometry. Methods: Two T1-weighted MPRAGE 3D datasets were acquired at 3T in thirty-seven children, median age 7.75 years; one with conventional linear phase encoding and one using DISORDER. MPRAGE images were scored as motion-free or motion-corrupt.