Barbara A Messerle

The Effect of the C5-Substituent on Regioselectivity in the Rh(I)-Catalyzed Intermolecular Transannulation of 1,2,3-Thiadiazoles with Phenylacetylene Marina A. Tokareva, Indrek Pernik, Barbara Messerle, Tatiana V. Glukhareva and Sinead Keaveney Abstract Despite the growing use of denitrogenative reactions of 1,2,3-thiadiazoles in heterocycle synthesis, the origin of the varied reactivity and divergent regioselectivity observed in their transannulation reactions is not well understood.

Controlling the Selectivity and Efficiency of the Hydrogen Borrowing Reaction by Switching Between Rhodium and Iridium Catalysts The catalytic alkylation of ketones with alcohols via the hydrogen borrowing methodology (HB) has the potential to be a highly efficient approach for forming new carbon-carbon bonds. However, this transformation can result in more than one product being formed.

Two highly versatile xanthene scaffolds containing pairs of heteroditopic ligands were found to be capable of accommodating a range of transition metal ions, including Au(I), Ir(I), Ir(III), Rh(I), and Ru(II) to generate an array of heterobimetallic complexes. The metal complexes were fully characterised and proved to be stable in the solid and solution state, with no observed metal-metal scrambling.